is a purine nucleoside antiviral drug extracted from Streptomyces culture medium and then prepared by chemical synthesis. It is a white crystalline powder, very slightly soluble in water, and its monophosphate ester is easily soluble in water. It has an inhibitory effect on DNA viruses such as herpes simplex virus HSV1 and HSV2, hepatitis B virus, varicella-zoster virus and cytomegalovirus, but has no effect on smallpox virus, adenovirus, other DNA or RNA viruses, bacteria and fungi. The exact antiviral mechanism of cytarabine has not been fully elucidated yet, and it is mainly related to inhibiting viral replication.
|
|
|
is mainly used to treat the induction and maintenance phases of acute lymphocytic and non-lymphocytic leukemia, the blast phase of chronic myeloid leukemia and the treatment of malignant lymphoma. It is used in ophthalmology to treat viral keratitis and epidemic conjunctivitis. It also has a certain effect on head and neck cancer, digestive tract cancer and lung cancer. In addition, this drug can inhibit the reproduction of herpes simplex virus, smallpox virus, vaccinia virus and the body's immune response.
In this article, an LC-MS/MS method is described for the determination of cytarabine in human plasma down to the sub ng/ml level. To prevent conversion of cytarabine by cytidine deaminase, whole blood samples were stabilized with tetrahydrouridine directly after the collection of whole blood at the clinical site. Cation-exchange SPE was employed to extract cytarabine from 50 µl human plasma. UHPLC on high strength silica T3 column (100 × 2.1 mm × 1.8 µm) was applied to achieve adequate separation of cytarabine from cytidine within a reasonable run time of 5 min.
| 99% | ||
| 100% pass 80 mesh | ||
| Less than or equal to 5.0% | 2.20% | |
| Less than or equal to 0.1% | 0.05% | |
| Less than or equal to 0.1% | ||
| Less than or equal to 0.5% | ||
| Less than or equal to 10ppm | ||
| Less than or equal to 0.1% | <0.1% | |
| Less than or equal to 3 ppm | ||
| <1000CFU/g | ||
| <100 CFU /g | ||
?
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
?
|
3-7 days |
|
Suitable for under 50kg. |
|
|
7-15 days |
Suitable for more than 50kg. |
||
|
15-60 days |
Suitable for more than 500kg. |
Népszerű tags: cytarabine powder cas 147-94-4, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China